生物医学工程学杂志

生物医学工程学杂志

介孔生物活性玻璃研究进展

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生物活性玻璃(BG)因其具有良好的成骨性能及生物活性,已成为骨组织工程领域的研究热点,但其仍然存在细胞黏附性差、载药量小等不足。介孔生物活性玻璃(MBG)是在生物活性玻璃和介孔二氧化硅(MS)基础上研制的新型材料,其内部存在大量的纳米级孔道,并具有更大的比表面积、更好的生物相容性及生物活性,因而在骨组织工程领域具有极大的应用前景。本文就介孔生物活性玻璃的制备及其实验研究进展作一综述,以期为相关研究提供理论基础与实验参考。

Bioactive glass (BG) has been widely used in bone tissue engineering due to its good osteogenic property and bioactivity, but it still has some deficiencies, such as poor cell adhesion and low osteogenic rate and so on. Mesoporous biological glass (MBG) is a kind of new material originated from BG and mesoporous silica (MS). Because of its large number of nano-channel, large specific surface area, easy degradation, good biocompatibility and biological activity, MBG has great application prospects in the field of bone tissue engineering. This review would present MBG preparation and experimental research in order to provide the theoretical basis and experimental reference for related researches.

关键词: 介孔生物活性玻璃; 生物活性; 骨组织工程

Key words: mesoporous bioactive glass; bioactivity; bone tissue engineering

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